Published clinical studies demonstrating Activia's beneficial effects on health
17 published clinical studies, including 7 on the strain survival and 10 on the benefit (6 related to transit and 4 to digestive comfort).
Published clinical studies on the survival of the Bifidobacterium animalis DN-173010.
- Rochet V, L Rigottier-Gois, A Ledaire, C Andrieux, M Sutren, S Rabot, A Mogenet, J-L Bresson, S Cools, C Picard, N Goupil-Feuillerat and J Doré.
Survival of Bifidobacterium animalis DN-173 010 in the faecal microbiota after administration in lyophilised form or in fermented product - a randomised study in healthy adults.
Journal of Molecular Microbiology and Biotechnology, 2008;14: 128-136. - He T, M G Priebe, Y Zhong, C Huang, HJM Harmsen, GC Raangs, JM Antoine, GW Welling and RJ Vonk.
Effect of yogurt and bifidobacteria supplementation on the colonic microbiota in lactose-intolerant subjects.
Journal of Applied Microbiology, 2007; 104(2):595-604. - Collado M.C., Y. Moreno, J.M. Cobo, J.A. Mateos, M. Hernandez.
Molecular detection of Bifidobacterium animalis DN-173 010 in human feces during fermented milk administration.
Food Research International, 2006; 39: 530-535. - Duez H, Pelletier C, Cools S, Aissi E, Cayuela C, Gavini F, Bouquelet S, Neut C and Mengaud J.
A colony-immunoblotting method for quatitative detection of a Bifidobacterium animalis probiotic strain in human faeces.
Journal of Applied Microbiology, 2000; 88:1019-27. - Pochart P, Marteau P, Bouhnik Y, Goderet I, Bourlioux P, Rambaud JC.
Survival of Bifidobacteria ingested via fermented milk during their passage through the human small intestine: an in vivo study using intestinal perfusion.
American Journal of Clinical Nutrition, 1992; 55:78-80. - Berrada N, Lemeland JF, Laroche G, Thouvenot P, Piaia M.
Bifidobacterium from fermented milks: Survival during gastric transit.
Journal of Dairy Science, 1991; 74:409-413. - Pochart P, Marteau P, Bisetti N, Goderet I, Bourlioux P, Rambaud JC.
Isolement des bifidobactéries dans les selles après ingestion prolongée de lait au bifidus (LB).
No abstract available
Médecine et Maladies Infectieuses 1990; 20: 75-78 (publication in French).
Published studies on transit
- This study is about both benefits, transit and digestive comfort
Agrawal A., Houghton L.A., Morris J., Reilly B.,D., Guyonnet D., Goupil-Feuillerat N., Schlumberger A., Jakob S. & Whorwell P.J.
Clinical trial: the effects of a fermented milk product containing Bifidobacterium lactis DN-173-010 on abdominal distension and gastrointestinal transit in irritable bowel syndrome with constipation.
Alimentary Pharmacology and Therapeutics, 2009; 29(1): 104-114. - Nishida S., Ishikawa Y., Iino H.
Effect of Bifidobacterium lactis DN-173 010 on the Intestinal Transit Time, the Condition of Defecation and Intestinal Microflora: A randomized, Double-blind, Placebo-controlled, Cross-over Study among Healthy Japanese Women.
Pharmacometrics 2008;74 (5/6) : 99-106. - Méance S, Cayuela C, Raimondi A, Turchet P, Lucas C and Antoine JM.
Recent advances in the use of functional foods: effects of the commercial fermented milk with Bifidobacterium animalis strain DN-173 010 and yoghurt strains on gut transit time in the elderly.
Microbial Ecology in Health and Disease 2003; 15: 15-22. - Marteau P, Cuillerier E, Méance S, Gerhardt MF, Myara A, Bouvier M, Bouley C, Tondu F, Bommelaer G, Grimaud JC.
Bifidobacterium animalis strain DN-173 010 shortens the colonic transit time in healthy women : a double blind, randomized, controlled study.
Alimentary Pharmacology and Therapeutics, 2002; 16: 587-593. - Méance S, Cayuela C, Turchet P, Raimondi A, Lucas C and Antoine JM.
A fermented milk with a Bifidobacterium probiotic strain DN-173 010 shortened oro-fecal gut transit time in elderly.
Microbial Ecology in Health and Disease. 2001; 13: 217-222. - Bouvier M, Méance S, Bouley C, Berta JL and Grimaud JC.
Effect of consumption of a milk fermented by the probiotic strain Bifidobacterium animalis DN-173 010 on colonic transit time in healthy humans.
Bioscience Microflora. 2001; 20 (2): 43-48.
Published studies on digestive comfort
- Guyonnet D., Schlumberger A., Mhamdi L., Jakob S., Chassany O.
Fermented milk containing Bifidobacterium lactis DN-173 010 improves gastrointestinal well-being and digestive symptoms in women reporting minor digestive symptoms: a randomised, double-blind, parallel, controlled study.
British Journal of Nutrition, 2009 Jul 22:1-9 [Epub ahead of print]. - Guyonnet D., Woodcock A., Stefani B., Trevisan C. and Hall C.
Fermented milk containing Bifidobacterium lactis DN-173 010 improved self-reported digestive comfort amongst a general population of adults. A randomized, open-label, controlled, pilot study.
Journal of Digestive Diseases, 2009; 10: 61-70. - This study is about both benefits, transit and digestive comfort.
Agrawal A., Houghton L.A., Morris J., Reilly B.,D., Guyonnet D., Goupil-Feuillerat N., Schlumberger A., Jakob S. & Whorwell P.J.
Clinical trial: the effects of a fermented milk product containing Bifidobacterium lactis DN-173-010 on abdominal distension and gastrointestinal transit in irritable bowel syndrome with constipation.
Alimentary Pharmacology and Therapeutics, 2009; 29(1): 104-114. - Guyonnet D, O. Chassany, P. Ducrotte, C. Picard, M. Mouret, C.H. Mercier and C. Matuchansky.
Effect of a fermented milk containing Bifidobacterium animalis DN-173 010 on the health-related quality of life and symptoms in irritable bowel symdrome adults in primary care. A multicentre, randomised, double-blind, controlled trial.
Alimentary Pharmacology and Therapeutics, 2007; 26 (3): 475-486.
Additional study on bowel functions
- Yang Y., He M., Hu G., Wei J., Pages P., Yang X., Bourdu-Naturel S.
Effect of a fermented milk containing Bifidobacterium animalis DN-173 010 on Chinese constipated women.
World Journal of Gastroenterology, 2008; 14(40): 6237-6243.
Only the abstracts of the articles are available. To get the full article, in accordance with copy-right rules, please request them directly from the journals concerned.